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Current Research Studies

ANALYZE-ST

ANALYZE-ST: Tests the accurary of the ST monitoring feature on Implantable Cardioverter Defibrillator (ICD). Sean Mazer, MD Principal Investigator


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CAMELLIA

Study to Evaluate the Effect of Long-Term Treatment with BELVIQ (lorcaserin HC1) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects with Cardiovascular Disease or Multiple Cardiovascular Risk Factors.  Brendan J. Cavanaugh, MD Principal Investigator


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CANTOS

A randomized, double-blind, placebo-controlled, eventdriven trial of quarterly subcutaneous canakinumab in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with elevated hsCRP.             Robert C. Orchard, MD Principal Investigator


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EVOLVE II

To assess the safety and effectiveness of the SYNERGY Coronary Stent System for the treatment of subjects with atherosclerotic lesion(s) < 34 mm in length (by visual estimate) in native coronary arteries >2.25 mm to < 4.0 mm in diameter (by visual estimate).  Geoff A. Kunz, MD Principal Investigator 


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LIFE

This study is a prospective, consecutively enrolling non-randomized multi center post market registry to evaluate the ultra-low profile (14F) Ovation Prime Abdominal Stent Graft System when used in the Percutaneous Endovascular Aneurysm Repair (P-EVAR) treatment of patient with AAA using a Fast-Track EVAR protocol     Steve A. Henao, MD Prinicipal Investigator


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LUTONIX BTK

Compared the Lutonix drug coated balloon vs. standard balloon angioplasty for treatment of below-the Knee (BTK) arteries. Steve A. Henao, MD Principal Investigator


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MULTIPOINT PACING (MPP)

Evaluation safety & efficiacy of the Quadripolar CRT-D device system when compared to standard Bi-V pacing. Ross A. Downey, MD Principal Investigator


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On-X VALVE

Compares the On-X valve on low dose anticoagulation to concomitant groups of On-X valves receiving standard coumadin/aspirin therapy and to also drive FDA objective performance criteria (OPC).  Brian D. Castlemain, MD Principal Investigator


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PARAGON

This study is a multi-center, randomized, double-blind, parallel group, active comparator, morbidity and mortality trial designed to evaluate the efficacy and safety of LCZ696 compared to valsartan in HFpEF patients(NYHA class II-IV). Robert Orchard, MD Principal Investigator


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REDUCE-IT

This study evaluates the effect of AMR101 on cardiovascular health and mortality in Hypertriglyceridemic patients with CAD or a high risk for CAD. Robert Orchard, MD Principal Investigator


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St. Jude's Leads Assessment (CLAS)

A study involving the Riata®/Riata® ST silicone endocardial leads made by St. Jude Medical.  This study does not involve any investigational product (medical device) or procedures.


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TEMPO

Dose Ranging Study to Evaluate the Effect of GS-6615 on Ventricular Arrhythmia in Subjects with Implantable Cardioverter-Defibrillator (ICD) or Cardiac Resynchronization Therapy (CRT). Ross A. Downey, MD Principal Investigator


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THEMIS

Study to Evaluate the Effect of Ticagrelor 90 mg Twice Daily on the Incidence of Cardiovascular Death, Mycocardial Infarction or Stroke in Patients with Type 2 Diabetes Mellitus.  Karen S. Sopko, MD Principal Investigator


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